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Personnel de recherche INSERM

M. William Raoul

Chargé de recherche Inserm

Coordonnées

Parc de Grandmont 37200 TOURS 37261 TOURS

Tél
0247366267
Mail
william.raoul@univ-tours.fr

Discipline(s)

Libellé inconnu

Activités / CV

2017: Habilitation à Diriger des Recherches, Oncologie, Université François-Rabelais de Tours

2005: Doctorat de Sciences de la Vie et de la Santé, Toxicologie, Université Paris XII-Créteil

2001: Diplôme d'études approfondies, Toxicologie, Université Paris V-Descartes

2000: Maîtrise de Biologie Cellulaire et Physiologie Animale, Université Paris XII-Créteil

Informations complémentaires

Guéguinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crottès D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores-Romero H, Lefèvre A, Lerondel S, Le Pape A, Dumas JF, Frank PG, Girault A, Chautard R, Guéraud F, García-Sáez AJ, Ouaissi M, Emond P, Sire O, Hérault O, Fromont-Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W*, Lecomte T*. Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell Mol Life Sci. 2022 May 8;79(6):284.

Chautard R, Corset L, Ibrahim S, Desvignes C, Paintaud G, Baroukh N, Guéguinou M, Lecomte T*, Raoul W*. Panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells. Biomark Med. 2021 Jun;15(10):685-696.

Ibrahim S, Chaigne J, Dakik H, Fourbon Y, Corset L, Lecomte T, Raoul W*, Guéguinou M*. SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer.  Cell Calcium. 2021 (96) 102384.

Ibrahim S, Dakik H, Vandier C, Chautard R, Paintaud G, Mazurier F, Lecomte T, Guéguinou M*, Raoul W*. Expression Profiling of Calcium Channels and Calcium-Activated Potassium Channels in Colorectal Cancer. Cancers. 2019 Apr 19;11(4).

Lereclus E, Tout M, Girault A, Baroukh N, Caulet M, Borg C, Bouché O, Ternant D, Paintaud G, Lecomte T, Raoul W. A possible association of baseline serum IL-17A concentrations with progression-free survival of metastatic colorectal cancer patients treated with a bevacizumab-based regimen. BMC Cancer. 2017 Mar 27;17(1):220.

Camelo S, Calippe B, Lavalette S, Dominguez E, Hur J, Devevre E, Guillonneau X, Raoul W*, Sennlaub F*. Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice. Mol Vis. 2015 21:1051-1059.

Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ, Dominguez E, Camelo S, Levy O, Guyon E, Saederup N, Charo IF, Rooijen NV, Nandrot E, Bourges JL, Behar-Cohen F, Sahel JA, Guillonneau X, Raoul W, Combadiere C. CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med. 2013 Nov;5(11):1775-93.

Lavalette S*, Raoul W*, Houssier M, Camelo S, Levy O, Calippe B, Jonet L, Behar-Cohen F, Chemtob S, Guillonneau X, Combadière C, Sennlaub F. Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration. Am J Pathol. 2011 May;178(5):2416-23.

Houssier M, Raoul W, Lavalette S, Keller N, Guillonneau X, Baragatti B, Jonet L, Jeanny JC, Behar-Cohen F, Coceani F, Scherman D, Lachapelle P, Ong H, Chemtob S, Sennlaub F. CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents. PLoS Med. 2008 Feb;5(2):e39.

Combadière C*, Feumi C*, Raoul W*, Keller N, Rodéro M, Pézard A, Lavalette S, Houssier M, Jonet L, Picard E, Debré P, Sirinyan M, Deterre P, Ferroukhi T, Cohen SY, Chauvaud D, Jeanny JC, Chemtob S, Behar-Cohen F, Sennlaub F. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest. 2007 Oct;117(10):2920-8.

Raoul W, Wagner-Ballon O, Saber G, Hulin A, Marcos E, Giraudier S, Vainchenker W, Adnot S, Eddahibi S, Maitre B. Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice. Respir Res. 2007 Jan 30;8:8.

Louzier V*, Raoul W*, Leroux A, Branellec D, Caillaud JM, Many H,  Levame M, Delclaux C, Adnot S, Maitre B. Adenovirus-mediated fibroblast growth factor 1 expression in the lung induces epithelial cell proliferation: consequences to hyperoxic lung injury in rats. Hum Gene Ther. 2004 Aug;15(8):793-804.

Raoul W, Chailley-Heu B, Barlier-Mur AM, Delacourt C, Maitre B, Bourbon JR. Effects of vascular endothelial growth factor on isolated fetal alveolar type II cells. Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6): L1293-301.