M. William Raoul

Chargé de recherche CRHC Inserm

UMR Inserm U 1069 - Niche, Nutrition, Cancer et métabolisme Oxydatif (N2COx)
UFR de Médecine

Coordonnées

Tél: 0247366267
Mail: william.raoul@univ-tours.fr
Site internet: https://cv.hal.science/william-raoul

Discipline(s)

Libellé inconnu

Activités / CV

2017: Habilitation à Diriger des Recherches, Oncologie, Université François-Rabelais de Tours

2005: Doctorat de Sciences de la Vie et de la Santé, Toxicologie pulmonaire, Université Paris XII-Créteil

2001: Diplôme d'études approfondies, Toxicologie générale, Université Paris V-Descartes

2000: Maîtrise, Biologie Cellulaire et Physiologie Animale, Université Paris XII-Créteil

Informations complémentaires

Victoir B, Pertegaz O, Ducrocq E, Polomski M, Guéguinou M, Raoul W, Croix C, Prié G. Synthesis and biological evaluation of new tri-heterocyclic derivatives as anti-colorectal cancer agents. Results in Chemistry. January 2025, 102015.

Robert A, Crottès D, Bourgeais J, Gueguen N, Chevrollier A, Dumas JF, Servais S, Domingo I, Chadet S, Sobilo J, Hérault O, Lecomte T, Vandier C, Raoul W, Guéguinou M. MICU2 up-regulation enhances tumor aggressiveness and metabolic reprogramming during colorectal cancer development. PLoS Biol. 2024 Oct 28;22(10):e3002854.

Chautard R, Caulet M, Bouché O, Borg C, Manfredi S, Capitain O, Spano JP, Raoul W, Guéguinou M, Herault O, Ferru A, Pobel C, Sire O, Lecomte T. Evaluation of serum mid-infrared spectroscopy as new prognostic marker for first-line bevacizumab-based chemotherapy in metastatic colorectal cancer. Dig Liver Dis. 2024 Aug 19:S1590-8658(24)00886-7.

Vilímová I, David S, Vigouroux C, Raoul W, Corset L, Misericordia Y, Chourpa I, Hervé-Aubert K. Fe3O4-Based Magnetic Nanoprobes for miRNA-484 Capture in Human Serum: Implications for Colorectal Cancer Screening. ACS Appl. Nano Mater. 2024, 7, 8, 8854–8861.

Roy M, Alix C, Burlaud-Gaillard J, Fouan D, Raoul W, Bouakaz A, Blanchard E, Lecomte T, Viaud-Massuard MC, Sasaki N, Serrière S, Escoffre JM. Delivery of Anticancer Drugs Using Microbubble-Assisted Ultrasound in a 3D Spheroid Model. Mol Pharm. 2024 Feb 5;21(2):831-844.

Romito O, Guéguinou M, Raoul W, Champion O, Robert A, Trebak M, Goupille C, Potier-Cartereau M. Calcium signaling: A therapeutic target to overcome resistance to therapies in cancer. Cell Calcium. 2022 Dec;108:102673.

Guéguinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crottès D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores-Romero H, Lefèvre A, Lerondel S, Le Pape A, Dumas JF, Frank PG, Girault A, Chautard R, Guéraud F, García-Sáez AJ, Ouaissi M, Emond P, Sire O, Hérault O, Fromont-Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W*, Lecomte T*. Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell Mol Life Sci. 2022 May 8;79(6):284.

Chautard R, Corset L, Ibrahim S, Desvignes C, Paintaud G, Baroukh N, Guéguinou M, Lecomte T*, Raoul W*. Panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells. Biomark Med. 2021 Jun;15(10):685-696.

Desvignes C, Ternant D, Lecomte T, Lièvre A, Ohresser M, Chautard R, Raoul W, Paintaud G. A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations. Bioanalysis. 2021 Apr;13(7):565-574.

Ibrahim S, Chaigne J, Dakik H, Fourbon Y, Corset L, Lecomte T, Raoul W*, Guéguinou M*. SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer. Cell Calcium. 2021 (96) 102384.

Guéguinou M, Pathak T, Robert A, Vandier V, Trebak M, Lecomte T, Raoul W. L’échangeur ionique NCLX : un rôle ambivalent dans la chronologie du cancer colorectal. médecine/sciences 2021 ; 37 : 124-126.

Oyallon B, Brachet-Botineau M, Logé C, Souab M, Robert T, Bach S, Ibrahim S, Raoul W, Berthelot P, Gouilleux F, Viaud-Massuard MC, Denevault-Sabourin C. New quinoxaline derivatives as dual Pim-1/Pim-2 inhibitors: design, synthesis and biological evaluation. Molecules. 2021 Feb 6;26(4):867

Potier-Cartereau M, Raoul W, Weber G, Mahéo K, Rapetti-Mauss R, Gueguinou M, Buscaglia P, Goupille C, Le Goux N, Abdoul-Azize S, Lecomte T, Fromont G, Chantome A, Mignen O, Soriani O & Vandier C. Potassium and calcium channel complexes as novel targets for research in cancer. Rev Physiol Biochem Pharmacol. 2020 Aug 8.

Dolly A, Dumas JF, Lecomte T, Bouché O, Borg C, Terrebonne E, Douillard JY, Chautard R, Raoul W, Ternant D, Leger J, Bleuzen A, Servais S, Baracos VE. Concurrent losses of skeletal muscle mass, adipose tissue and bone mineral density during bevacizumab / cytotoxic chemotherapy treatment for metastatic colorectal cancer. Clinical nutrition. 2020 Feb 22:S0261-5614(20)30080-7.