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Our new article in Nature ! microbial supply chain for production of the anti-cancer drug vinblastine from Jie Zhang Lea G. Hansen Olga Gudich Catharanthus roseus which is then followed by simple in vitro chemical coupling and reduction to form vinblastine catharanthine using a highly engineered yeast and in vitro chemical coupling to vinblastine. The study pyrophosphate and tryptophan to catharanthine and vindoline. In total 56 genetic edits were performed including expression collaborators. Dr Vincent Courdavault , assistant professor in our lab and Emily A. Stander, former post-doctoral researcher are co-authors of this paper published in Nature. Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr Dr Emily Stander France 3 Région CvdL microbial supply chain for production of the anti-cancer drug vinblastineArticle - 21/09/22
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using fluorescence in situ hybridization FISH analysis. This relevant strategy resulted in the most contiguous elucidation of the biosynthesis of the plant anticancer drug camptothecin by Emily Amor Stander Thomas Dugé de elucidation which is unfortunately severely missing in species naturally accumulating camptothecin. This high-quality genomic resources of medicinal plant species. In such a perspective Yamazaki and colleagues produced Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr recent Ophiorrhiza pumila genome assembly published in Computational and Structural Biotechnology Journal pathway leading to the production of the anticancer drug campthotecin. elucidation of the biosynthesis of the plant anticancer drug camptothecinActualité - 21/02/22
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Adaptation in urban areas Adaptation in urban areas Adaptation in urban areasActualité - 06/05/20
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Adaptation in urban areas Adaptation in urban areas Adaptation in urban areasActualité - 02/12/19
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Maintenance Scheduling in the Wind IndustryArticle - 23/11/16
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Recent advances in optimization based software developmentArticle - 10/12/17
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Workshop Hormones and Behaviors in Arthropods 2018 Si le lien entre hormones et comportements est largement arthropodes. Programme détaillé et inscription ICI Email marlene.goubault@univ-tours.fr Workshop "Hormones and Behaviors in Arthropods" 2018Article - 14/05/19
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témoignages de personnes ayant été droguées à leur insu au GHB ont mis en lumière une situation exceptionnelle portant Campagne de prévention GHBPage libre - 21/03/22
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energy policy in its history. This case study sheds light on the dynamics of public policy in contemporary instruments in addressing a wicked public policy issue. Energy matters have long stood in a grey zone CECILLE autour de son ouvrage Nuclear Power Policies in Britain the Quandaries of Neoliberalism Anthem Press Britain s most recent nuclear power project initiated in the mid-2000s within the context of growing national Nuclear Power Policies in BritainActualité - 13/10/25