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engineered microbial systems for compound synthesis. In this regard yeasts remain the easiest-tractable eukaryotic dedicated to the bioproduction of new-to-nature compounds in yeasts and provide an overview of emerging strategies Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast.

[International Workshop] Glossy Glosses in Latin and Vernacular Manuscripts

stress and point out some lags in our understanding of its involvement in the virulence of pathogenic species The high osmolarity glycerol HOG pathway in fungi from Yaakoub H Sanchez NS Ongay-Larios L Courdavault many species are responsible for devastating mycosis in humans. Such niche diversity explains how quick fungal apparatus underpinning fungal adaptation and virulence. In this review we summarize the seminal knowledge of improve the fungal-based production of natural products in the industry. Keywords Fungi phosphorylation signalling stress, and point out some lags in our understanding of its involvement in the virulence of pathogenic species The high osmolarity glycerol (HOG) pathway in fungi

insights into the biosynthetic route of KA in red algae and DA in diatoms the DA biosynthetic pathway has active research in this area to gain insights into secondary biosynthetic pathways in marine organisms Towards a Better Understanding of Toxin Biosynthesis in Seaweeds. Chembiochem. 2022 Aug 17 23 16 e202200223 represent both ecological and public health hazards in the marine environment. Indeed some algae can produce has remained uncharacterized for red algae. In a recent work the research groups of Chekan and Moore have Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr We discuss in this Highlight article the importance of continuing to acquire new data on biosynthetic biosynthetic pathways in marine organisms for both diagnostic and metabolic-engineering purposes. Towards a Better Understanding of Toxin Biosynthesis in Seaweeds

Convergent evolution for antibiotic biosynthesis in bacteria and animals from Papon N Courdavault V Medema ability to biosynthesize antimicrobial polyketides in parallel with bacteria. spotlight in Trends in genetics about the convergent evolution for antibiotic biosynthesis in bacteria Convergent evolution for antibiotic biosynthesis in bacteria and animals

peroxisomes in the context of spatial reconfiguration and compile the recent breakthrough in yeast peroxisome Peroxisomes A New Hub for Metabolic Engineering in Yeast by Natalja Kulagina Sébastien Besseau Nicolas with native components. To address such an issue in heterologous production the peroxisome progressively including the work of Gerhard H. Braus' team published in this special issue which demonstrate the remarkable Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr First publication from MIACYC project in Frontiers in Bioengineering and Biotechnology! The article shed peroxisomes in the context of spatial reconfiguration and compile the recent breakthrough in yeast peroxisome Peroxisome : a new hub for metabolic engineering in yeast

guidelines for microclimate research in terrestrial ecosystems. Methods in Ecology and Evolution 16 269 294 Nouvel article dans "Methods in Ecology and Evolution"

stressors modulate aggressive behavior Current Opinion in Insect Science Volume 71 2025 101407 ISSN 2214-5745 Nouvel article dans "Current Opinion in Insect Science"

these pathways. Herein we review emerging approaches in biosynthetic pathway elucidations and their prospects Emerging trends in plant natural products biosynthesis: a chemical perspective

at very low levels in several Tabernaemontana species. Unfortunately genome data in Tabernaemontanaceae metabolism in plants. These gene discoveries also allowed us to engineer the synthesis of MIAs in yeast through Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans. Plant J. 2024 Oct 20. doi of active molecules some of which have been used in human health for decades. Among these monoterpene knowledge on the biogenesis of pachysiphine-related MIAs in planta remains scarce limiting the prospects for Dr Vincent Courdavault email vincent.courdavault@univ-tours.fr with medicinal properties, could be harnessed for drug production. The researchers sequenced the genome identifying key enzymes and engineering MIA production in yeast, this study opens the door to new biotechnological Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans